Biomin launches first purified enzyme against fumonisins

Fumzyme, the first purified enzyme that biotransforms fumonisins into non-toxic metabolites, will be launched during VIV Asia 2013 in Bangkok, Thailand. Fumzyme is a purified enzyme that biotransforms fumonisins into non-toxic metabolites in the gastrointestinal tract of animals. The detoxifying activity of this revolutionary enzyme was confirmed in numerous in vitro and in vivo experiments.

“Fumonisins elicit a toxic effect on the sphingolipid metabolism. The ratio of the sphingoid bases sphinganine and sphingosine in serum serves as an indicator (biomarker) of the effects of fumonisin on animals” says Ursula Hofstetter, director of the Competence Center Mycotoxins at Biomin. “For the first time, using the sphinganine/sphingosine ratio (Sa/So) as a biomarker, the detoxification of fumonisins by FUMzyme can be clearly demonstrated” continues Hofstetter. Read more...